Research Article

Anti-Inflammation Property of Syzygium cumini (L.) Skeels on Indomethacin-Induced Acute Gastric Ulceration

Table 1

Malondialdehyde (MDA), oxidized glutathione (GSSG), glutathione peroxidase (GPx), nitrite contents, gastric wall mucus, and plasma TNF- in gastric tissue of SCC acute test group.

ParameterGroup 1Group 2Group 3Group 4Group 5Group 6Group 7

Mucus
(µg Alcian blue/g wet stomach)
19.35 ± 0.9415.78 ± 0.33a,c20.74 ± 0.75b21.13 ± 0.98b23.59 ± 0.55a,b,c21.31 ± 0.75a,b16.28 ± 0.64a,c

MDA
Plasma 
(nM/mL)
17.97 ± 2.6923.99 ± 2.49a,c16.54 ± 5.53b16.45 ± 4.04b,c16.01 ± 3.19b,c19.06 ± 2.35a,b19.17 ± 2.55a,b
Tissue 
(nM/mg tissue)
1.18 ± 0.111.55 ± 0.03a,c1.07 ± 0.29b1.03 ± 0.12b0.92 ± 0.04a,b1.04 ± 0.14b1.29 ± 0.06a,b,c

GSSG
(ng/mg Protein)
0.75 ± 0.011.26 ± 0.04a,c0.99 ± 0.04a,b0.87 ± 0.05a,b,c0.81 ± 0.01a,b,c0.98 ± 0.04a,b0.87 ± 0.01a,b,c

GPx
(U/g Protein)
2.41 ± 0.370.75 ± 0.19a,c1.17 ± 0.13a,b,c1.19 ± 0.16a,b,c2.59 ± 0.13b,c0.99 ± 0.05a,b0.89 ± 0.04a,b,c

Nitric oxide
(nM/mg Protein)
1.02 ± 0.312.39 ± 0.49a,c1.27 ± 0.311b,c1.07 ± 0.37b,c0.68 ± 0.23a,b,c1.54 ± 0.18a,b0.78 ± 0.11b,c

Plasma TNF-
(pg/mL)
1.71 ± 0.042.09 ± 0.13a2.07 ± 0.09a,c1.92 ± 0.05a1.83 ± 0.03a,b1.89 ± 0.05a1.80 ± 0.06a,b

compared with normal mice group, when compared with indomethacin treated group, and when compared with omeprazole treated group.