Research Article

Herbal Substance, Acteoside, Alleviates Intestinal Mucositis in Mice

Table 2

Histological severity scores for C57BL/6 mice (/group) treated with PS, PM, AS, and MA.

TreatmentDuodenumJejunumIleum
d 5d 11d 5d 11d 5d 11

PS2.5 (2, 5)3 (1, 6)2.5 (1, 4)5 (2, 9)3 (1, 5)1 (1, 5)
AS2.5 (1, 3)2 (1, 6)3 (2, 7)3 (2, 4)1.5 (1, 4)2 (0, 2)
PM13 (2, 16)*2 (1, 4)#13 (10, 18)*6 (2, 10)#13 (7, 15)*1 (0, 3)#
MA3 (2, 5)2.5 (1, 6)2.5 (2, 4)3 (1, 8)1 (1, 3)1 (1, 4)

Data was expressed as median and range in parenthesis. *Statistical significance compared to all other groups () on d 5. #Statistical significance () compared to d 5. PS = PBS + saline, AS = acteoside + saline, PM = PBS + MTX, and MA = MTX + acteoside.