Clinical Outcome of Patients with Complete Pathological Response to Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancers: The Indian Scenario

Table 1

Demographic and clinicopathological characteristics.

Characteristics	= 64 (%)
Gender
Male	42 (65.6%)
Female	22 (34.4%)
Age (yr)
Range	18–77
Median	47
Stage at presentation^a
cT3N0	39 (60.9%)
cT4N0	2 (3.1%)
cT3N+^x	23 (35.9%)
Distance from anal verge (AV)^b
AV-2 cms	25 (39.1%)
2–5 cms	15 (23.4%)
5–10 cms	20 (31.3%)
>10 cms	04 (6.3%)
Pretreatment CEA (ng/mL)^c
Range	1.1–127
Median	3.2
Surgery
Abdominoperineal resection (APR)^d	29 (45.3%)
Low anterior resection	10 (15.6%)
Anterior resection	22 (34.3%)
Intersphincteric resection	03 (4.6%)
Histology
Classical adenocarcinoma	50 (78.1%)
Mucinous adenocarcinoma	5 (7.8%)
Signet cell adenocarcinoma	9 (14.06%)
Extracellular mucin pool
Yes	24 (37.5%)
No	40 (62.5%)
Total nodes dissected
Range	1–21
Median	08
Radiotherapy type
Long course	67 (95.7%)
Short course	03 (4.3%)
Radiotherapy dose
50 GY	48 (75%)
40–45 GY	14 (22%)
25 GY	02 (3.1%)
Laparoscopy
Yes	11 (17.2%)
No	53 (82.8%)
Interval of NACTRT to surgery (days)
Range	12–206
Median	56.5
Postoperative chemotherapy
Yes	39 (60.9%)
No	25 (39.1%)

Clinicoradiological staging.
^bAV: anal verge.
^cCEA: carcinoembryonic antigen.
^dAPR indicates abdominoperineal resection.
^xN+: positive nodal status.