Eradication of Helicobacter pylori Is Associated with the Progression of Dementia: A Population-Based Study

Table 2

The effect of H. pylori eradication on the progression of dementia.

	1538 demented people with PU (ICD-9:290.xx & ICD-9:531–534)
	H. pylori eradication		Percentage, %	OR, (95% CI)	Adjusted OR, (95% CI)
	Yes	No
Medication change (+)	472	690	79.95	0.58 (0.46–0.74)	0.34 (0.23–0.52)
Medication change (−)	203	173	20.05	1	1

PU: peptic ulcer. OR: odds ratio. We estimated odds ratio of progression of dementia by 𝜒² test.
We estimated adjusted odds ratio by multiple linear regression, adjusted with age, gender, diabetes mellitus, hypertension, cerebrovascular disease and TIA, congestive heart failure, coronary artery disease, and hyperlipidemia.