Immunohistochemistry for collagen type IV (a) and α-smooth muscle actin- (α-SMA-) positive cells in the pancreas on day 14 after the induction of PDH. (a) Type IV collagen deposition was observed as irregular and discontinuous lines along the basement membrane of the ducts. In addition, broad deposition of type IV collagen was observed around the ducts. (b) α-SMA-positive cells were detected in the periductal, periacinar, and interstitial areas. Original magnification ×200.
