Cytogenetics and Molecular Genetics of Myxoid Soft-Tissue Sarcomas
Figure 1
(a) Myxoid liposarcoma with a myxoid background containing a delicate arborizing capillary vascular network, small uniform mesenchymal cells, and lipoblasts. (b) G-banded karyotype showing a 12; 16 translocation as the sole aberration. (c) Fluorescence in situ hybridization analysis using a DDIT3 (12q13) break-apart probe shows a split of the orange and green signals, indicating a disruption of the DDIT3 locus.
