Review Article
A Guided Tour of the Structural Biology of Gaucher Disease: Acid-β-Glucosidase and Saposin C
Table 2
Structures of saposin C.
| PDB code | Enzyme source | Detergent? | Technique | Experimental summary | Citation |
| 1M12 | E. coli | No | NMR | 15N, 1H, and 13C heteronuclear NMR experiments | [45] | 1SN6 | E. coli | Yes, SDS | NMR | 15N, 1H, and 13C heteronuclear NMR experiments | [75] | 2GTG | E. coli | No | Crystallography | Calcium chloride, Hepes buffer pH 7 or cacodylate buffer pH 6, glycerol cryoprotectant | [78] | 2QYP | P. pastoris | No | Crystallography | Magnesium sulfate or ammonium sulfate, acetate buffer pH 4, pentaerythritol ethoxylate 15/4 | [50] | 2Z9A | P. pastoris | No | Crystallography | Same as 2QYP | [50] |
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