Evidence-Based Complementary and Alternative Medicine

Antimicrobial and Antioxidant Activities of Natural Compounds


Status
Published

1Sapienza Università di Roma, Rome, Italy

2University of Ferrara, Ferrara, Italy

3Johannes Gutenberg University, Mainz, Germany


Antimicrobial and Antioxidant Activities of Natural Compounds

Description

Since ancient times, medicinal plants have traditionally been used for the treatment of different diseases. Nowadays, plants are considered a valuable source of unique natural compounds used in the development of antidiabetic, anti-inflammatory, anticancerous, and antimicrobial drugs. Bacteria, fungi, and viruses are responsible for a range of human diseases. Microbial invasion and its virulence can cause damage to the host cells. Effective antimicrobials have been developed over the years; however, a dramatic increase in resistance to antimicrobial drugs has been observed. The resistance to these drugs has also led to the reemergence of old infectious diseases. Oxidative stress is characterized as an imbalance between the production of reactive species and antioxidant defense activity, and its enhanced state has been associated with many of the chronic diseases such as cancer, diabetes, and neurodegenerative and cardiovascular diseases. Many studies have investigated the antioxidant properties of natural products, but despite the large number of natural products that are currently studied, the search for new natural compounds with antimicrobial and antioxidant activities still remains a growing research area.

This special issue aims to highlight the recent research on new trends and on new antimicrobial and antioxidant natural compounds obtained from medicinal plants. Both in vitro and in vivo studies with the aim of relating antimicrobial and antioxidant properties of extracts, fractions, synergistic mixtures, and single pure compounds to possible treatments of human disorders and diseases are encouraged. We also welcome the submission of research articles studying the chemical structure of extracts, fractions, and isolated pure compounds. We invite authors who are leading experts in the field to contribute original articles that are not yet published or that are not currently under review by other journals. This special issue intends to provide a forum for researchers to share their recent findings and offer exposure of the published articles to the scientific community. We hope that this special issue will advance knowledge and stimulate new collaborations as well as research directions.

Potential topics include but are not limited to the following:

  • New antimicrobial and antioxidant natural compounds
  • Mechanism of action of antimicrobial or antioxidant natural compounds
  • Novel nanoparticles for the delivery of natural compounds active against microorganism and stress oxidative
  • Synergistic activity of natural compounds
  • Combination strategies between natural compounds and conventional therapeutic approaches
  • Pharmacological evidences (in vitro, in vivo, and in silico) related to antioxidant and antimicrobial activities
  • Multiple methodological approaches for the determination of antimicrobial and antioxidant properties
  • Antioxidant activities and inflammation-related disorders and diseases
  • Antimicrobial activities and drug-resistance phenomena

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 1945179
  • - Editorial

Antimicrobial and Antioxidant Activities of Natural Compounds

Letizia Angiolella | Gianni Sacchetti | Thomas Efferth
  • Special Issue
  • - Volume 2018
  • - Article ID 3207973
  • - Research Article

Effect of Allicin against Ischemia/Hypoxia-Induced H9c2 Myoblast Apoptosis via eNOS/NO Pathway-Mediated Antioxidant Activity

Lina Ma | Shangke Chen | ... | Hao Li
  • Special Issue
  • - Volume 2018
  • - Article ID 2325659
  • - Research Article

Toxicity, Phytochemical Composition, and Enzyme Inhibitory Activities of Some Indigenous Weed Plant Extracts in Fruit Fly, Drosophila melanogaster

Bushra Riaz | Muhammad Kashif Zahoor | ... | Kishwar Sultana
  • Special Issue
  • - Volume 2018
  • - Article ID 6743862
  • - Research Article

Evaluation of the In Vitro and In Vivo Antioxidant Potentials of Sudarshana Powder

Weerakoon Achchige Selvi Saroja Weerakoon | Pathirage Kamal Perera | ... | Thusharie Sugandhika Suresh
  • Special Issue
  • - Volume 2018
  • - Article ID 3438453
  • - Research Article

The Synergy and Mode of Action of Cyperus rotundus L. Extract Plus Ampicillin against Ampicillin-Resistant Staphylococcus aureus

Prairadda Cheypratub | Wilairat Leeanansaksiri | Griangsak Eumkeb
  • Special Issue
  • - Volume 2018
  • - Article ID 5124735
  • - Research Article

Syzygium jambos Displayed Antibacterial and Antibiotic-Modulating Activities against Resistant Phenotypes

Brice E. N. Wamba | Paul Nayim | ... | Victor Kuete
  • Special Issue
  • - Volume 2018
  • - Article ID 8248323
  • - Research Article

Ecklonia cava Extract and Dieckol Attenuate Cellular Lipid Peroxidation in Keratinocytes Exposed to PM10

Jeong-won Lee | Jin Kyung Seok | Yong Chool Boo
  • Special Issue
  • - Volume 2018
  • - Article ID 2738489
  • - Research Article

Seasonal Effect on the Biological Activities of Litsea glaucescens Kunth Extracts

Julio César López-Romero | Humberto González-Ríos | ... | Javier Hernández
  • Special Issue
  • - Volume 2018
  • - Article ID 1463579
  • - Research Article

Bioactivities of Traditional Medicinal Plants in Alexandria

Hosam O. Elansary | Agnieszka Szopa | ... | Diaa O. El-Ansary
  • Special Issue
  • - Volume 2018
  • - Article ID 2706417
  • - Research Article

Isolation and Identification of Compounds from Bioactive Extracts of Taraxacum officinale Weber ex F. H. Wigg. (Dandelion) as a Potential Source of Antibacterial Agents

Katy Díaz | Luis Espinoza | ... | Rolando Chamy
Evidence-Based Complementary and Alternative Medicine
 Journal metrics
Acceptance rate28%
Submission to final decision71 days
Acceptance to publication44 days
CiteScore2.010
Impact Factor1.984
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