[Retracted] Growth Differentiation Factor 7 Prevents Sepsis-Induced Acute Lung Injury in Mice

Figure 3

GDF7 reduces LPS-stimulated inflammation and oxidative stress in primary macrophages. (a) Primary peritoneal macrophages were pretreated with rmGDF7 (10 nmol/L) for 24 h and then stimulated with LPS (100 ng/mL) for another 6 h. Cell medium was collected for the analysis of IL-6 and TNF-α (n = 6). (b) ROS content in macrophages (n = 6). (c) MDA and 4-HNE levels in macrophages (n = 6). (d-e) Total SOD activity and GSH content in macrophages (n = 6). All data were presented as mean ± SD, and  < 0.05 was regarded to be statistically significant.

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