Research Article
RNA-Seq Profiling to Investigate the Mechanism of Qishen Granules on Regulating Mitochondrial Energy Metabolism of Heart Failure in Rats
Figure 4
QSG through PGC-1α/NRF1/TFAM signaling pathway improved myocardial mitochondrial biogenesis. (a) Effects of QSG on JC-1 on H9C2 cells after OGD/R. (b) Effects of QSG on the expression of PGC-1α, NRF1, and TFAM on H9C2 cells after OGD/R. (c) QSG regulated the balance of mitochondrial fusion (e.g., MFN1/2, OPA1) and fission (DRP1) on H9C2 cells after OGD/R. , , n = 3.
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