Skin Hydration Effects of Scale-Up Fermented <i>Cyclopia intermedia</i> against Ultraviolet B-Induced Damage in Keratinocyte Cells and Hairless Mice

<div>Effect of HU-018 on UVB irradiation-induced epidermal thickening in the dorsal skin of hairless mice. (a) Hematoxylin and eosin-stained images of UVB-irradiated dorsal skin of mice. The number (<i>μ</i>m) is the epidermal thickness. (b) Protective effects of HU-018 on photoaging of the skin regarding changes in collagen fiber volume determined using Masson’s trichrome staining. Collagen fibers are stained in blue, and images were obtained under 200x magnification. Scale bar = 100 <i>μ</i>m. HU-018, scaled-up fermented honeybush extract; UVB, ultraviolet B. Normal, non-irradiated group; vehicle, UVB-irradiated group.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: Skin Hydration Effects of Scale-Up Fermented <i>Cyclopia intermedia</i> against Ultraviolet B-Induced Damage in Keratinocyte Cells and Hairless Mice 

Figure 5 | Skin Hydration Effects of Scale-Up Fermented Cyclopia intermedia against Ultraviolet B-Induced Damage in Keratinocyte Cells and Hairless Mice 