A Traditional Clinic Chinese Medicine Prescription Qu-Zhuo-Tong-Bi (QZTB) Alleviates Gouty Arthritis in Model Rats

Figure 3

QZTB attenuated second injections of MSU crystal-induced recurrence of arthritis pain-like behavior and mechanical allodynia. Diagram of the experiment (a). Effects of pretreatment of QZTB (500 mg/kg·bw) and meloxicam (3 mg/kg·bw) on ankle swelling (b), pain-like behavior scores (c), and paw withdrawal thresholds (d) after the second injection of MSU crystal; the normalized inhibition ratio of QZTB and meloxicam (behavior scores after the second injection/first injection of MSU) (e–g). , , MSU + QZTB vs. MSU + vehicle; , MSU + meloxicam vs. MSU + vehicle. One-way analysis of variance (ANOVA) was used followed by Dunnett’s tests (n = 6–8).

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