Research Article
Suppressive Effect of Huzhentongfeng on Experimental Gouty Arthritis: An In Vivo and In Vitro Study
Table 2
Effect of HZTF and Tongfengshu on the ankle joint edema of MSU crystal-induced rats.
| Treatment | Dose (g/kg) | n | Foot-swelling values (cm, mean ± SD) | 1 h | 2 h | 3 h | 4 h | 5 h | 6 h | 7 h |
| Ctrl | — | 10 | 0.009 ± 0.002 | 0.010 ± 0.004 | 0.008 ± 0.003 | 0.0010 ± 0.003 | 0.004 ± 0.002 | 0.005 ± 0.001 | 0.003 ± 0.000 | MSU alone | — | 10 | 0.169 ± 0.055 | 0.185 ± 0.056 | 0.208 ± 0.065 | 0.254 ± 0.059 | 0.289 ± 0.058 | 0.323 ± 0.051 | 0.304 ± 0.061 | Tongfengshu | 1.50 | 10 | 0.107 ± 0.023 | 0.142 ± 0.046 | 0.161 ± 0.042 | 0.193 ± 0.049 | 0.202 ± 0.048 | 0.253 ± 0.053 | 0.239 ± 0.055 | HZTF | 0.25 | 10 | 0.139 ± 0.035 | 0.178 ± 0.050 | 0.197 ± 0.051 | 0.206 ± 0.056 | 0.226 ± 0.055 | 0.257 ± 0.028 | 0.247 ± 0.065 | HZTF | 0.50 | 10 | 0.123 ± 0.042 | 0.150 ± 0.056 | 0.168 ± 0.056 | 0.204 ± 0.060 | 0.218 ± 0.041 | 0.245 ± 0.025 | 0.237 ± 0.062 | HZTF | 1.00 | 10 | 0.121 ± 0.048 | 0.135 ± 0.044 | 0.150 ± 0.042 | 0.179 ± 0.037 | 0.197 ± 0.038 | 0.217 ± 0.034 | 0.189 ± 0.050 |
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when compared with MSU groups, when compared with MSU groups. |