Dandelion Root and Lemongrass Extracts Induce Apoptosis, Enhance Chemotherapeutic Efficacy, and Reduce Tumour Xenograft Growth In Vivo in Prostate Cancer
Figure 6
Dandelion root and lemongrass extracts administered orally reduce the tumour burden on prostate cancer xenograft mice. DU-145 (a) and PC-3 (b) prostate cancer cells were xenografted onto immunocompromised mice hind flanks subcutaneously. After tumour formation, these mice were orally fed dandelion root (DRE) and lemongrass (LGE) extract for 8 weeks. After mice were sacrificed, tumours (top panels) were excised and measured for tumour volume (using the formula 1/2(LW2) to calculate approximate volume) and tumour weight. (c) Mouse body mass was measured two times a week and averaged to compare between control, DRE, and LGE groups. Statistical calculations were performed using One-Way ANOVA multiple comparison. p < 0.05 vs. control, p < 0.01 vs. control, p < 0.0001 vs. control. No markings indicate nonsignificance vs. control.