Dandelion Root and Lemongrass Extracts Induce Apoptosis, Enhance Chemotherapeutic Efficacy, and Reduce Tumour Xenograft Growth In Vivo in Prostate Cancer

Figure 2

Dandelion root and lemongrass extracts are selective for cancer and reduce toxicity of chemotherapeutics. Normal colon mucosa (NCM) cells were treated with various dosages of DRE, LGE, and DRE or LGE combination treatments with taxol and assessed at 48 hours. Results were obtained using image-based cytometry to assess the percentage of cells positive with fluorescence associated with Annexin V (green), propidium iodide (PI, red), both (yellow), or negative for both Annexin V and PI (blue). Values are expressed as a mean ± SD from three independent experiments. Statistical calculations were performed using Two-Way ANOVA multiple comparison. p < 0.05 vs. control, p < 0.01 vs. control, p < 0.0001 vs. control, @p<0.05 vs. individual chemotherapy treatment.