Research Article

Multiresponse Optimization of Pomegranate Peel Extraction by Statistical versus Artificial Intelligence: Predictive Approach for Foodborne Bacterial Pathogen Inactivation

Table 4

Statistics test of main and interaction effects of univariate mixed analyses of variance for all dependent variables and effects (Trial and Time) with 95% confidence intervals.

OutcomeEffectLevel numberParameter numberFdfnum/dfden value

Fixed trial
Anti-S. aureus activityIntercept11206.0941/60<0.001
Time20190.65719/600.845
Trial1166.1871/60<0.001
Time × trial20191.29119/600.224
Anti-S. enterica activityIntercept1166.1711/601.000
Time20190.24019/600.412
Trial1184.1221/60<0.001
Time × trial20191.54019/600.104

Fixed time
Anti-S. aureus activityIntercept111226.2291/90<0.001
Trial1146.6541/90<0.001
Time543.6164/900.009
Trial × time5495.2304/90<0.001
Anti-S. enterica activityIntercept11387.7031/90<0.001
Trial1121.0931/90<0.001
Time541.2284/900.305
Trial × time5415.2254/90<0.001

dfnum/dfden = degrees of freedom of numerator/denominator.