Research Article

Metabolomics-Based Clinical Efficacy and Effect on the Endogenous Metabolites of Tangzhiqing Tablet, a Chinese Patent Medicine for Type 2 Diabetes Mellitus with Hypertriglyceridemia

Table 1

The comparison of baseline characteristics among three groups (mean ± S.D.).

VariableTZQ-F GroupPlacebo GroupAcarbose Group
(n=15)(n=15)(n=16)

Sex (M/F)8/712/39/7
Age (year)62.93±6.1157.40±9.7458.07±5.23
BMI (kg/m2)26.99±3.1728.56±3.8725.90±2.27
Waistline (cm)95.43±11.24100.23±8.3694.87±8.44
HbA1c (%)7.64±0.817.59±1.037.25±0.79
FINS (mIU/L)16.64±8.6515.00±7.0715.10±14.57
FBG (mmol/L)7.44±1.177.75±1.077.62±1.17
OGTT2hBG (mmol/L)13.96±4.0213.76±3.1513.91±4.68
TG (mmol/L)1.52±0.612.06±1.052.35±1.38
TC (mmol/L)4.92±0.704.87±0.824.74±0.78
LDL-C (mmol/L)2.86±0.522.87±0.612.59±0.63
HDL-C (mmol/L)1.38±0.391.17±0.251.22±0.35

Note: data were analyzed using ANOVA. p>0.05 (among three groups). FBG: fasting blood glucose; OGTT 2hBG: oral glucose tolerance test 2 h blood glucose; HbA1c: glycosylated hemoglobin; BMI: body mass index; TC: total cholesterol; TG: triglyceride; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol.