Clinical Pharmacology of Citrus aurantium and Citrus sinensis for the Treatment of Anxiety

Table 6

Clinical trials quality assessment according to Jadad score.

	Authors	Was the trial; described as randomized?	Was the; randomization; procedure; described and appropriate?	Was the trial; described as double-blind?	Was the method; of double blinding; described and; appropriate?	Was the; number of; withdrawals/dropouts; in each group mentioned?	Jadad Score
Citrus aurantium	Fernandes Pimenta et al., 2016	Yes	Yes	No	No	No	2
	Chaves Neto et al., 2017	Yes	No	No	No	No	1
	Namazi et al., 2014	Yes	Yes	No	No	Yes	3
	Pei-Hsin et al., 2010	Yes	No	No	No	No	0
	Hasheminia et al., 2014	Yes	Yes	No	No	No	2
	Akhlaghi et al., 2011	Yes	Yes	Yes	Yes	Yes	5
Citrus sinensis	Lehrner et al., 2000	Yes	No	No	No	No	0
	Jaafarzadeh et al., 2017	Yes	Yes	Yes	No	Yes	3
	Costa Goes et al., 2012	Yes	Yes	Yes	No	Yes	3

The JADAD scoring system was used for the assessment of randomized controlled trials with the following 5 items:
Was the study described as randomized? (Yes = 1 point, No = 0 points);
Was the randomization scheme described and appropriate? (Yes = 1 point, No = -1 point);
Was the study described as double-blind? (Yes = 1 point, No = 0 points);
Was the method of double blinding appropriate? (Yes = 1 point, No = -1 point. If the answer of Item 3 was No, Item 4 is not calculable);
Was there a description of dropouts and withdrawals? (Yes = 1 point, No = 0 points).