The Synergy and Mode of Action of Cyperus rotundus L. Extract Plus Ampicillin against Ampicillin-Resistant Staphylococcus aureus

Table 3

MICs and FICI of CRE and ampicillin when used either alone or in combination against S. aureus strains.

Strains		MIC		FIC	FICI
	AMP (g/ml)	CRE (mg/ml)	NIS (g/ml)	AMP+ CRE (g/ml + mg/ml)
S. aureus DMST 20651	64	0.5	16	1.0 + 0.125	0.27
S. aureus DMST 20652	64	0.5	16	1.0 + 0.125	0.27
S. aureus DMST 20653	64	0.5	16	1.0 + 0.125	0.27
S. aureus ATCC 29213	0.25	0.25	0.5	NT	NT

S. aureus ATCC 29213 was used as a reference strain; was the lowest FIC value; was the lowest FICI value. ; ; interaction. data in CLSI; NT = no test; AMP = ampicillin; CRE = Cyperus rotundus extract; NIS = nisin.