Antidiarrheal Activity of 80% Methanolic Leaf Extract of Justicia schimperiana

Table 1

Effect of methanolic leaf extract of J. schimperiana on castor oil-induced diarrhea in mice.

Group	Dose; (mg/kg)	Onset of diarrhea (min)	Total number of feces	% inhibition of	Weight of stool (g)	Total number of diarrheal feces	% inhibition of diarrhea^#
Group 1 (negative control)	-			-			-
Group 2 (positive control)	3			77.99			80.06
Group 3 (extract)	100			38.99			42.58
Group 4 (extract	200			50.84			65.07
Group 5 (extract)	400			72.04			74.96

Values expressed as mean ± SEM (); compared with the negative control; inhibition is relative to the negative control group. Negative control: a group of mice that received distilled water. Positive control: a group of mice treated with loperamide.