Research Article

Preventive Effects of Velvet Antler (Cervus elaphus) against Lipopolysaccharide-Induced Acute Lung Injury in Mice by Inhibiting MAPK/NF-κB Activation and Inducing AMPK/Nrf2 Pathways

Figure 1

The effects of the aqueous extract of velvet antler (AVA) on histopathological changes in the lung (a) and on the severity of lung injury were analyzed using the lung injury scoring system (b) in LPS-induced ALI mice. Mice were sacrificed 6 h after LPS stimulation. The right lungs were excised and embedded in 10% formalin, sectioned, and stained with H&E (magnification ×400). Images are representative of three experiments. Dex: dexamethasone. The data are presented as the mean ± SD for three different experiments performed in triplicate. with the control group. and compared with the LPS-alone group.
(a)
(b)