A Review of Black Salve: Cancer Specificity, Cure, and Cosmesis

Table 1

Black salve constituent normal cell cytotoxicity.

Compound	Cell type	IC50 (μM)	Ref
Sanguinarine	Skin fibroblasts KF-II	1	[32]
	Gingival fibroblasts	1.2	[33]
	Epidermal keratinocytes	10	[34]
Chelerythrine	Skin fibroblasts KF-II	1.5	[32]
	Gingival fibroblasts	4.7	[33]
Sanguilutine	Lung fibroblasts	1.2	[35]
Chelilutine	Lung fibroblasts	1.7	[35]
Sanguirubine	Skin fibroblasts KF-II	0.53	[32]
Chelirubine	Skin fibroblast KF-II	0.5	[32]
Zinc chloride	Murine fibroblast	0.93	[36]
NDGA	HaCaT keratinocytes	150	[37]