Astragalus Granule Prevents Ca2+ Current Remodeling in Heart Failure by the Downregulation of CaMKII
Effect of AG on modulation relative protein kinase. (a) Quantification of CaMKII and p-PKA expression levels (). (b) Representative western blots. ((c)–(e)) Typical traces at 0.1 Hz and 1.0 Hz from the sham (c), TAC (d), and TAC + AG groups (e). (f) The variance ratio of peak between 0.1 Hz and 1.0 Hz from each group (). versus sham group, versus TAC group; red arrow and blue arrow indicate positive and negative frequency-dependent facilitation, respectively.
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