Skin Wound Healing Potential and Mechanisms of the Hydroalcoholic Extract of Leaves and Oleoresin of Copaifera langsdorffii Desf. Kuntze in Rats

Figure 5

Gene expression by RT-qPCR of COL1A1, COL3A1, EGF, FGF-2, and TGF-β1 in skin wounds treated for 3, 7, and 14 days with Lanette, Collagenase, 10% EH, or 10% OR. The gene expression was normalized according toβ-ACTIN gene. , , and , compared with Lanette. , compared with Collagenase, using ANOVA followed by Newman-Keuls test ().