Long-Term Effects of TCM Yangqing Kangxian Formula on Bleomycin-Induced Pulmonary Fibrosis in Rats via Regulating Nuclear Factor-κB Signaling

Figure 9

Phosphorylation protein levels of cytoplasm IKKβ and IκBα and nuclear NF-κB in bleomycin-induced pulmonary fibrosis rats treated with Yangqing Kangxian formula, prednisone, or pirfenidone. (a) Phosphorylations of cytoplasm IKKβ and IκBα protein; (b) phosphorylations of nuclear NF-κB p65 protein; (c) phosphorylations of cytoplasm IKKβ protein; (d) phosphorylations of cytoplasm IκBα protein; (e) phosphorylations of nuclear NF-κB p65 protein. BLM: bleomycin; YKF: Yangqing Kangxian formula; PD: prednisone; PF: pirfenidone. . Values represented as mean ± SEM. and , versus BLM group. and , versus BLM + YKF group. and , versus BLM + PD group; and , versus BLM + PF group.

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