The Therapeutic Effects of the Chinese Herbal Medicine, Lang Chuang Fang Granule, on Lupus-Prone MRL/lpr Mice

Figure 3

The effects of LCF granule on protein expression of p65 NF-κB, Sirt1, and Nrf2 in the kidney tissues of MRL/lpr mice. Western blot analysis was performed to detect the protein expression of p65 NF-κB, Sirt1, and Nrf2 in the kidney tissues of MRL/lpr mice. MRL/lpr: lupus model group; LCF Low: low dose of LCF granule group (0.97 g/kg/d); LCF Medium: medium dose of LCF granule group (1.95 g/kg/d); LCF High: high dose of LCF granule group (3.90 g/kg/d). Data are expressed as fold change over the control group (means ± SDs, ). , versus MRL/lpr.