Herbal Medicine Cordyceps sinensis Improves Health-Related Quality of Life in Moderate-to-Severe Asthma
Table 3
Lung function scores and serum cytokines levels at baseline and immediately following the intervention period.
Control group ()
Treatment group ()
Baseline
Postintervention
Baseline
Postintervention
Lung function
FEV1 predicted, %
56.50 (33.40, 63.62)
60.50 (36.25, 66.87)
58.50 (40.75, 68.00)
63.10 (43.70, 72.60)c
2.442
0.015
PEFR, %
48.05 (33.45, 71.27)
50.50 (34.55, 64.85)
58.30 (36.62, 65.65)
59.09 (44.82, 67.70)c
2.525
0.012
FEV1/FVC predicted, %
57.54 (47.74, 71.29)
56.68 (45.96, 75.33)
54.01 (44.22, 63.00)
57.36 (49.77, 67.67)bc
2.162
0.031
Serum biomarkers
IgG (mg/mL)
58.59 (31.45, 85.93)
61.77 (30.59, 84.78)
40.53 (24.99, 50.78)
45.74 (38.43, 57.45)bc
2.459
0.014
IgE (ng/mL)
19.37 (15.75, 30.51)
24.82 (19.84, 47.65)
31.22 (16.44, 51.27)
26.21 (22.63, 31.90)bd
3.655
0.000
ICAM-1 (ng/mL)
266.43 (209.99, 314.51)
324.34 (257.65, 400.17)
313.12 (255.55, 363.66)
291.35 (233.08, 311.71)ad
4.462
0.000
IL-4 (pg/mL)
60.67 (32.92, 79.50)
63.00 (35.75, 75.15)
65.60 (46.67, 77.00)
47.33 (30.67, 64.67)bc
2.529
0.011
IFN-γ (pg/mL)
8.45 (7.25, 9.15)
8.40 (5.85, 9.35)
9.00 (6.20, 12.00)
8.50 (7.20, 11.80)
1.126
0.260
MMP-9 (ng/mL)
537.50 (256.43, 626.34)
644.64 (379.24, 626.34)
719.64 (504.46, 1238.88)
410.63 (272.62, 657.14)bd
5.092
0.000
Data are medium (IQR). and Postinterventions. Baseline; and CS group versus control group. FEV1 (%): forced expiratory volume in one second (percentage of predicted). PEF (%): mean peak expiratory flow (% predicted). FVC: forced vital capacity.