The Score Model Containing Chinese Medicine Syndrome Element of Blood Stasis Presented a Better Performance Compared to APRI and FIB-4 in Diagnosing Advanced Fibrosis in Patients with Chronic Hepatitis B
Table 3
Comparison between the patients with advanced fibrosis and without advanced fibrosis.
Variables
Patients without advanced fibrosis
Patients with advanced fibrosis
value
()
()
Demographic characteristics
Age (years) (X ± SD)
37.9 ± 9.7
42.2 ± 10.6
<0.001
Males, (%)
315 (66.0%)
171 (73.7%)
0.039
Laboratory data
ALT (IU/L) (X ± SD)
35.9 ± 17.8
37.7 ± 16.9
0.205
AST (IU/L) (X ± SD)
27.9 ± 11.9
34.3 ± 17.9
<0.001
ALB (g/L) (X ± SD)
44.4 ± 3.9
44.6 ± 26.1
0.819
GGT (IU/L) (X ± SD)
27.3 ± 19.8
47.4 ± 55.9
<0.001
PLT (109/L) (X ± SD)
203.7 ± 53.2
161.7 ± 50.0
<0.001
HBeAg (+) patients, (%)
238 (49.9%)
93 (40.1%)
0.014
HBV DNA (log10 IU/mL, X ± SD)
5.55 ± 2.09
5.08 ± 1.75
0.004
TCM syndrome elements
Dampness
471 (98.7%)
226 (97.4%)
0.198
Qi stagnation
438 (91.8%)
213 (91.8%)
0.780
Blood stasis
84 (17.6%)
227 (97.8%)
<0.001
Heat
269 (56.4%)
35 (15.1%)
<0.001
Qi deficiency
101 (21.2%)
72 (31.0%)
0.004
Yin deficiency
4 (0.8%)
3 (1.3%)
0.566
ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALB, albumin; GGT, g-glutamyl transpeptidase; PLT, platelet; HBeAg, hepatitis B e antigen; TCM, Traditional Chinese Medicine.
