Evidence-Based Complementary and Alternative Medicine / 2016 / Article / Tab 1 / Research Article
The Score Model Containing Chinese Medicine Syndrome Element of Blood Stasis Presented a Better Performance Compared to APRI and FIB-4 in Diagnosing Advanced Fibrosis in Patients with Chronic Hepatitis B Table 1 Characteristics of 709 CHB patients with ALT < 2ULN.
Variables All patients 0 < ALT ≤ 40 40 < ALT ≤ 80 valueDemographic characteristics Age (years), median (IQR) 39.0 (31.5–46.0) 39.0 (32.0–45.0) 38.0 (31.0–47.0) 0.823 Males, (%) 486 (68.5%) 273 (62.6%) 213 (78%) <0.001 Laboratory data ALT (IU/L), median (IQR) 35.0 (22.0–47.0) 25.0 (18.0–33.0) 51.0 (45.0–64.0) <0.001 AST (IU/L), median (IQR) 26.0 (21.0–36.0) 22.6 (19.0–27.0) 36.0 (30.0–43.0) <0.001 ALB (g/L), median (IQR) 44.1 (42.0–46.4) 43.9 (42.0–46.1) 44.4 (41.95–46.85) 0.280 GGT (IU/L), median (IQR) 24.0 (17.5–38.0) 21.0 (15.0–33.0) 31.0 (22.0–45.0) <0.001 PLT (109 /L), median (IQR) 186 (152.0–224.0) 187 (151.0–223.0) 185 (152.0–225.0) 0.828 HBeAg (+), (%) 331 (46.7%) 178 (40.8%) 153 (56.0%) <0.001 HBV DNA (log10 IU/mL), median (IQR) 5.49 (3.62–7.21) 4.72 (3.24–6.79) 6.29 (4.98–7.59) <0.001 Liver histology Inflammation activity, (%) G0–2, (%) 600 (84.6%) 380 (63.3%) 220 (36.7%) 0.018 G3-4, (%) 109 (15.4%) 56 (51.4%) 53 (48.6%) Fibrosis (%) F0–2, (%) 477 (67.3%) 296 (62.1%) 181 (37.9%) 0.661 F3-4, (%) 232 (32.7%) 140 (60.3%) 92 (39.7%)
ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALB, albumin; GGT, g-glutamyl transpeptidase; PLT, platelet; HBeAg: hepatitis B e antigen; IQR, interquartile range.