Research Article

Intake of Novel Red Clover Supplementation for 12 Weeks Improves Bone Status in Healthy Menopausal Women

Table 5

Inflammatory markers before (week 0) and after (week 12) the intervention in the two groups, RC and placebo.

RCPlacebo
Week 0Week 12 valueaWeek 0Week 12 valuea

IL-1b, pg/mL16.8 (±0.9)16.6 (±0.9)18.3 (±1.2)15.9 (±1.1)
IL-2, pg/mL93.9 (±3.7)93.4 (±4.2)103.3 (±5.7)94.9 (±6.6)
IL-4, pg/mL13.5 (±0.7)13.3 (±0.7)15.2 (±0.9)13.4 (±1.0)
IL-5, pg/mL101.1 (±6.8)107.5 (±6.8)104.4 (±7.9)97.4 (±8.0)
IL-6, pg/mL21.5 (±0.9)22.54 (±1.2)25.0 (±1.6)23.2 (±1.6)
IL-10, pg/mL18.4 (±0.9)17.4 (±0.8)19.6 (±1.0)18.1 (±1.1)
IL-12, pg/mL18.8 (±0.9)18.0 (±0.9)20.5 (±1.1)18.5 (±1.3)
IL-13, pg/mL15.5 (±0.9)16.0 (±0.9)17.2 (±1.1)15.5 (±1.1)
IFN-gamma, pg/mL33.1 (±1.6)32.3 (±1.6)35.5 (±1.8)35.1 (±2.1)

Representing value within-group differences between week 0 and week 12. Data are presented as mean (±SEM).