Traditional Uses, Phytochemistry, and Pharmacology of Olea europaea (Olive)

Table 7

Anti-inflammatory and antinociceptive activities of Olea europaea.

S. no.	Part/type of extract/compound	Disease/assay	Animal model	Effective dose	Reference drug	Reference
1	Oleanolic acid	Antinociceptive	Female CD-1 mice (Barcelona, Spain)	—	Ibuprofen, pregabalin, baclofen	[232]
2	Olive oil	Antinociceptive and anti-inflammatory	Male Balb/C mice	10 mg/Kg	Dexamethasone	[231]
3	n-Hexane extract of fruits	Anti-inflammatory and antinociceptive	Male Swiss albino mice	400 mg/Kg	Indomethacin, acetylsalicylic acid	[136]
4	Olive oil	Analgesic and anti-inflammatory	Male Wistar rats	100–300 mg/Kg	Acetyl salicylate of lysine	[135]
5	n-Hexane extract of fruit	Anti-inflammatory and antinociceptive	Male Swiss albino mice	400 mg/Kg	Indomethacin, acetylsalicylic acid	[136]
6	Ethanolic extract of dry leaves	Antinociceptive, antihyperalgesic	Male Wistar rats	200 mg/Kg	Morphine	[230]
7	EVOO, Oleocanthal	Ibuprofen like activity	In vitro	—	Ibuprofen	[229]