Research Article

Anti-Inflammatory Property of Plantago major Leaf Extract Reduces the Inflammatory Reaction in Experimental Acetaminophen-Induced Liver Injury

Table 1

Effects of three different P. major leaf extracts on aspartate aminotransferase (AST) and alanine aminotransferase (ALT) enzymes at day 1 and day 7 after APAP induction.

GroupsAST at day 1
U/L
AST at day 7
U/L
ALT at day 1
U/L
ALT at day 7
U/L

Control109.67 ± 1.74133.50 ± 1.4452.17 ± 1.4170.00 ± 0.67
APAP223.97 ± 3.36a145.33 ± 1.73c109.58 ± 1.78a77.58 ± 0.43c
APAP + AQ254.11 ± 3.80a137.25 ± 1.97c94.58 ± 1.20a 55.33 ± 0.58b
APAP + MT219.33 ± 2.98a158.00 ± 1.06c117.75 ± 1.39a74.92 ± 0.63c
APAP + ET174.17 ± 3.37a106.33 ± 1.16c103.08 ± 1.3a74.42 ± 0.82c

Significant difference from the control group of the same day ().
bSignificant difference from the APAP group of the same day ().
cSignificant difference between the same group of day 1 and day 7 ().