A Special Extract of Bacopa monnieri (CDRI-08) Restores Learning and Memory by Upregulating Expression of the NMDA Receptor Subunit GluN2B in the Brain of Scopolamine-Induced Amnesic Mice

Figure 4

Acetylcholinesterase activity in prefrontal cortex (a) and hippocampus (b). Tissues obtained from 6-7 mice of each group were pooled and AChE activity was assayed. The AChE activity was expressed as unit/min/mg tissue. Data represents mean ± SEM. C, control; BME (Bacopa monnieri extract), CDRI-08-treated; SC, scopolamine-treated; SC + BME, scopolamine-treated mice treated with CDRI-08 as in Figure 2. and #, and ## and , were considered significant. , comparison between control and other groups. #, comparison between SC and remaining groups.

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