Olive Leaf Extract Attenuates Obesity in High-Fat Diet-Fed Mice by Modulating the Expression of Molecules Involved in Adipogenesis and Thermogenesis

Table 1

Composition of the experimental diets.

Ingredients	HFD; (g/kg diet)	OLD; (g/kg diet)	SD; (g/kg diet)
Casein	200	200	200
DL-methionine	3	3	3
Corn starch	111	109.5	110.9
Sucrose	370	370	370
Cellulose	50	50	50
Corn oil	30	30	30
Lard	170	170	170
Mineral mixture^1	42	42	42
Vitamin mixture^2	12	12	12
Choline bitartrate	2	2	2
Cholesterol	10	10	10
tert-Butylhydroquinone^3	0.04	0.04	0.04
Olive leaf extract	—	1.5	—
Sibutramine	—	—	0.1
Total (g)	1,000	1,000	1,000
Fat (% calories)	40	40	40
Total energy (kcal/kg diet)	4,616	4,616	4,616

1AIN-76A mineral mix.
2AIN-76A vitamin mix.
3Antioxidant agent: 0.01 g/50 g lipids.