Olive Leaf Extract Attenuates Obesity in High-Fat Diet-Fed Mice by Modulating the Expression of Molecules Involved in Adipogenesis and Thermogenesis
Figure 5
Effects of OLE on the expression of genes involved in thermogenesis in the epididymal adipose tissue of HFD-fed mice. (a) The expression of genes involved in uncoupled respiration and mitochondrial biogenesis was determined by RT-PCR and normalized to that of GAPDH; (b) protein levels of p-CREB and total CREB were determined by western blotting and normalized to β-actin protein levels. Data represent the results of three independent experiments ( or 3 per experiment); indicates statistical significance. Values are the means ± SEM, for each group.
