Validation of the Antidiabetic and Hypolipidemic
Effects of Clitocybe nuda by Assessment of Glucose
Transporter 4 and Gluconeogenesis and AMPK
Phosphorylation in Streptozotocin-Induced Mice
Figure 1
Effects of extract of Clitocybe nuda on (a) the levels of blood glucose in STZ induced acute test, (b) final body weight, (c) visceral fat weight, (d) blood glucose levels, (e) the glycosylated hemoglobin (HbA1c) levels, (f) circulating triglyceride levels, and (g) leptin levels at the end of experiment in STZ induced chronic test. All values are means S.E. (). #P < 0.05, ##P < 0.01, and ###P < 0.001 compared with the control (CON) group; *P < 0.05, **P < 0.01, and ***P < 0.001 compared with the streptozotocin + vehicle (distilled water) (STZ) group. C1, C2, and C3: extracts of Clitocybe nuda (C1: 0.2, C2: 0.5, and C3: 1.0 g/kg bodyweight); Metf: metformin (0.3 g/kg body weight). The HbA1c is represented by % hemoglobin.
