Research Article

Oral Administration of MBG to Modulate Immune Responses and Suppress OVA-Sensitized Allergy in a Murine Model

Figure 3

The comparison of cytokine concentrations (IL-4, IL-5, TNF-α, IL-2, and IFN-γ) in serum and splenocyte cultured fluid from the B6 mice administered with MBG in different dosages for 6 weeks. As shown in (a) and (c), concentrations of IL-4 and TNF-α were significantly decreased among MBG treatment groups. In contrary, concentrations of IL-2 and IFN-γ were significantly increased among MBG treatment groups ((d) and (e)). Each value represents the mean ± SD from ten independent experiments. Statistical significance was indicated by Duncan’s test; the different letters represent a significant difference between the groups ( ). PC: positive control, low: low dose, med.: medium, high: high dose.
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(a)
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(b)
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(c)
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(d)
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(e)