Oral Administration of MBG to Modulate Immune Responses and Suppress OVA-Sensitized Allergy in a Murine Model
Figure 3
The comparison of cytokine concentrations (IL-4, IL-5, TNF-α, IL-2, and IFN-γ) in serum and splenocyte cultured fluid from the B6 mice administered with MBG in different dosages for 6 weeks. As shown in (a) and (c), concentrations of IL-4 and TNF-α were significantly decreased among MBG treatment groups. In contrary, concentrations of IL-2 and IFN-γ were significantly increased among MBG treatment groups ((d) and (e)). Each value represents the mean ± SD from ten independent experiments. Statistical significance was indicated by Duncan’s test; the different letters represent a significant difference between the groups (). PC: positive control, low: low dose, med.: medium, high: high dose.