Anti-Inflammatory and Antiosteoclastogenic Activities of Parthenolide on Human Periodontal Ligament Cells In Vitro

Figure 3

Effect of PTL on the expression of MMP-2 and MMP-9. (a) Expression of MMP-2; (b) expression of MMP-9. hPDLCs were treated with PTL (1 and 5 μM) for 1 and 3 days and then total protein and RNA were collected. The abundance of proteins was detected by Western blot. GAPDH was included as a loading control. The intensities of the bands were measured with densitometry and first normalized to GAPDH and then further converted to the percentage of the control (containing medium only). Error bars indicate mean ± SEM (). versus the control while versus the LPS group.

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