Anti-Inflammatory and Antinociceptive Activities of Untreated, Germinated, and Fermented Mung Bean Aqueous Extract
Table 1
Effect of oral administration of MB, GMB, and FMB aqueous extracts on heat induced paw licking in mice. Acetyl salicylic acid (ASA) (400 mg/kg) was used as reference drug. (Unit = seconds.)
Treatment
Dose (mg/kg)
Latency period (minute)
Before treatment
After treatment
0
30
60
90
120
Control (normal saline)
0
13.0 ± 0.10
11.2 ± 0.70
11.7 ± 0.91
10.8 ± 0.30
9.5 ± 0.71
MB
200
13.9 ± 0.75
13.8 ± 1.07
13.7 ± 0.95
14.3 ± 0.50*
13.3 ± 0.80
MB
1000
13.8 ± 0.10
13.3 ± 0.90
14.5 ± 0.25*
15.9 ± 0.80*
12.6 ± 1.05
GMB
200
13.5 ± 0.38
14.9 ± 0.20*
13.9 ± 0.51
15.4 ± 0.84*
18.2 ± 0.70*
GMB
1000
13.3 ± 0.26
13.8 ± 0.85
14.4 ± 0.75*
17.0 ± 1.09*
18.4 ± 0.68*
FMB
200
13.7 ± 0.55
14.1 ± 0.15
15.8 ± 1.03*
15.2 ± 1.00*
12.5 ± 0.55
FMB
1000
13.5 ± 0.75
14.2 ± 1.30
15.5 ± 0.35*
18.0 ± 1.29*
14.1 ± 0.65
ASA
400
13.4 ± 0.60
14.5 ± 1.00*
16.8 ± 0.53*
17.2 ± 0.80*
15.1 ± 1.70*
Note: Values are mean ± SEM (n = 6) and significantly different from control (*P < 0.05) by ANOVA and followed by Duncan’s multiple range test.
