Antibiotic Use in Children with Acute Respiratory or Ear Infections: Prospective Observational Comparison of Anthroposophic and Conventional Treatment under Routine Primary Care Conditions
Table 6
Odds ratios for main outcomes.
Outcome
Outcome rate
Unadjusted odds ratio (A- vs. C-)
Adjusted odds ratio (A- vs. C-)
A-Group
C-Group
= 443
= 86
value
OR
(95%-CI)
OR
(95%-CI)
%
%
No antibiotics days 0–28
421
95.0%
64
74.4%
<0.001
6.58
(3.45–12.56)
6.33
3.17
12.64
No analgesics days 0–28
429
96.8%
64
74.4%
<0.001
10.53
(5.13–21.63)
12.11
5.50
26.69
First improvement ≤24 hours
168
37.9%
17
19.8%
0.003
2.48
(1.41–4.36)
2.57
1.40
4.72
First improvement ≤3 days
358
80.8%
57
66.3%
0.019
2.14
(1.29–3.55)
1.88
1.10
3.23
Response on day 7
373
84.2%
54
62.3%
<0.001
3.16
(1.90–5.24)
3.34
1.93
5.79
Response on day 14
417
94.1%
74
86.0%
0.020
2.60
(1.26–5.38)
2.53
1.18
5.44
Recovery on day 7
155
35.0%
26
30.2%
0.457
1.24
(0.75–2.05)
1.19
0.68
2.07
Recovery on day 14
322
72.7%
50
58.1%
0.010
1.92
(1.19–3.09)
1.98
1.18
3.32
Very satisfied with treatment*
316
71.3%
36
36.0%
<0.001
3.46
(2.15–5.56)
4.15
2.50
6.86
Choosing this therapy again*
435
98.2%
65
75.6%
<0.001
17.57
(7.47–41.31)
18.92
7.65
46.81
Main outcomes: outcome rates, unadjusted odds ratios (OR) with 95% confidence intervals, and odds ratios after multiple logistic regression analysis, adjusting for gender, age, chief complaint, duration of complaint, complaint episode within last 12 months, baseline symptom score, and concomitant disease present at baseline. Odds ratio >1 indicates better outcome in A-group. *at all available follow-ups.
