Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Tab 1

Review Article

Honey: A Potential Therapeutic Agent for Managing Diabetic Wounds

Table 1

Successful clinical evidence of using honey on diabetic wounds (2005–2014).

NumberAge of diabetic patient (years)SexClinical complicationsType of honeyCourse of treatmentResolution timeReference (country, year)

152MalePostoperative (amputation) right foot ulcerNatural honeyOnce daily4 weeks[139] (Qatar, 2014)

2Male: 54.6 ± 12.7 (Mean ± SD) MaleWagner grades II, III, and IV diabetic foot ulcers Diabetic foot ulcers Manuka honey Once daily 11 days [130] (Saudi Arabia, 2013)
Female: 58.7 ± 13.4 (Mean ± SD)Female

355MaleDiabetic foot ulcerNatural honeyOnce daily4 weeks[140] (Qatar, 2012)

448MalePostoperative (amputation) right foot woundHoney-based gelTwice weekly2 months[141] (Portugal, 2011)

587FemalePostoperative (amputation) left foot woundHoney-based gelOnce daily4 weekshttp://www.l-mesitran.com/sites/l-mesitran.com/files/c120.pdf (2011)

652.3 (Mean) ()56.7% MaleDiabetic woundPure raw untreated commercial honeyOnce daily2.3 weeks (mean)[142] (Egypt, 2010)

746 (Mean) ()8 MaleWagner types I, II, III, and IVNatural honeyInitially once a dayFast excellent recovery[143] (Pakistan, 2009)

852.1 (Mean) ()15 MaleWagner grade II diabetic foot ulcersCommercial honey Once daily 14.4 days [126] (Malaysia, 2008)
15 Female

965MaleDiabetic foot woundA paste made of honey, propolis, and myrrhOnce daily4 weeks[131] (Saudi Arabia, 2006)

1079MaleDiabetic foot ulcerSupermarket honeyOnce daily6 months[144] (USA, 2005)

1162MaleDiabetic foot ulcerManuka honeyTwice weekly54% reduced by 4 weeks[121] (Ireland, 2005)