Review Article
Honey: A Potential Therapeutic Agent for Managing Diabetic Wounds
Table 1
Successful clinical evidence of using honey on diabetic wounds (2005–2014).
| Number | Age of diabetic patient (years) | Sex | Clinical complications | Type of honey | Course of treatment | Resolution time | Reference (country, year) |
| 1 | 52 | Male | Postoperative (amputation) right foot ulcer | Natural honey | Once daily | 4 weeks | [139] (Qatar, 2014) |
| 2 | Male: 54.6 ± 12.7 (Mean ± SD) | Male | Wagner grades II, III, and IV diabetic foot ulcers Diabetic foot ulcers |
Manuka honey |
Once daily |
11 days |
[130] (Saudi Arabia, 2013) | Female: 58.7 ± 13.4 (Mean ± SD) | Female |
| 3 | 55 | Male | Diabetic foot ulcer | Natural honey | Once daily | 4 weeks | [140] (Qatar, 2012) |
| 4 | 48 | Male | Postoperative (amputation) right foot wound | Honey-based gel | Twice weekly | 2 months | [141] (Portugal, 2011) |
| 5 | 87 | Female | Postoperative (amputation) left foot wound | Honey-based gel | Once daily | 4 weeks | http://www.l-mesitran.com/sites/l-mesitran.com/files/c120.pdf (2011) |
| 6 | 52.3 (Mean) () | 56.7% Male | Diabetic wound | Pure raw untreated commercial honey | Once daily | 2.3 weeks (mean) | [142] (Egypt, 2010) |
| 7 | 46 (Mean) () | 8 Male | Wagner types I, II, III, and IV | Natural honey | Initially once a day | Fast excellent recovery | [143] (Pakistan, 2009) |
| 8 | 52.1 (Mean) () | 15 Male | Wagner grade II diabetic foot ulcers | Commercial honey |
Once daily |
14.4 days |
[126] (Malaysia, 2008) | 15 Female |
| 9 | 65 | Male | Diabetic foot wound | A paste made of honey, propolis, and myrrh | Once daily | 4 weeks | [131] (Saudi Arabia, 2006) |
| 10 | 79 | Male | Diabetic foot ulcer | Supermarket honey | Once daily | 6 months | [144] (USA, 2005) |
| 11 | 62 | Male | Diabetic foot ulcer | Manuka honey | Twice weekly | 54% reduced by 4 weeks | [121] (Ireland, 2005) |
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