Targeted Metabolomics of Serum Acylcarnitines Evaluates Hepatoprotective Effect of Wuzhi Tablet (Schisandra sphenanthera Extract) against Acute Acetaminophen Toxicity

Figure 9

PPAR-targeted gene expression in livers from control, WZ-treated, WZ/APAP-treated, and APAP-treated mice. Liver samples were collected at 2 h and 24 h after APAP treatment. The gene expression levels were measured by real-time PCR and normalized by β-actin. Gene expression level in control mice was arbitrarily set as 1 (𝑛=5 in each group). *𝑃<0.05, compared to the control.

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