Effect of Korean Herbal Medicine Combined with a Probiotic Mixture on Diarrhea-Dominant Irritable Bowel Syndrome: A Double-Blind, Randomized, Placebo-Controlled Trial

Figure 3

Proportion of responders^† among all eligible patients using the intention-to-treat principle, according to treatment group assignment. Compared with GJS-P plus DUO-P group, GSJ plus DUO group, GJS-P plus DUO group, and GJS plus DUO-P group showed statistically significant improvement during 8 weeks of administration period. ^†Proportion of responders: proportion of patients who showed adequate relief of overall irritable bowel syndrome symptoms on at least half of the total weekly assessments (range: 0-1). GJS: Gwakhyangjeonggisan, DUO: Duolac7S, GJS-P: placebo of Gwakhyangjeonggisan, DUO-P: placebo of Duolac7S, *𝑃<0.05, **𝑃<0.01.