Research Article
Differential Localization of Pain-Related and Pain-Unrelated Neural Responses for Acupuncture at BL60 Using BOLD fMRI
Table 1
Activated and deactivated brain areas during the sham acupuncture before and after anesthesia.
| | | Area | Side | KE | peak | score |
| Sham > base
(pre-anesthetic) | Cortex | | | | | | Frontal lobe, inferior frontal gyrus | L | 213 | 6.81 | 4.73 | | Frontal lobe, inferior frontal gyrus | R | 685 | 7.49 | 4.98 | Temporal lobe, superior temporal gyrus
BA 22 | L | 2341 | 10.87 | 5.97 | Temporal lobe, superior temporal gyrus
BA 22 | R | 3103 | 8.64 | 5.57 | Parietal lobe, inferior parietal lobule
| L | 2341 | 7.05 | 4.82 | Limbic lobe, cingulate gyrus
BA 24 | L | 10039 | 9.13 | 5.51 | | Sublobar, claustrum | L | 793 | 8.34 | 5.27 | | Sublobar, caudate | L | 533 | 6.91 | 4.77 | | Cerebellum | | | | | | Anterior lobe, culmen | L | 10039 | 9.07 | 5.49 |
| Sham > base
(post-anesthetic) | Cortex | | | | | | Occipital lobe, precuneus | L | 54 | 4.63 | 3.71 | Temporal lobe, middle temporal gyrus
| L | 10 | 4.61 | 3.70 | | Cerebellum | | | | | | Anterior lobe, culmen | L | 37 | 4.05 | 3.37 |
| Sham < base
(pre-anesthetic) | Cortex | | | | | | Frontal lobe, precentral gyrus | L | 37 | 4.19 | 3.46 | Parietal lobe, postcentral gyrus
BA 3 | L | 37 | 4.19 | 3.46 |
| Sham < base
(post-anesthetic) | Cortex | | | | | | Occipital lobe, middle occipital gyrus | L | | | | | | | 59 | 4.77 | 3.79 | | | | 63 | 4.46 | 3.62 | Frontal lobe, precentral gyrus
BA 6 | L | 27 | 4.25 | 3.49 |
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(cluster level) < 0.001, cluster size ≥ 10 voxels.
Sham: sham acupuncture; base: baseline visual stimulation by showing a video clip of a leg; R: right; L: left; KE: expected voxels per cluster.
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