Chimonanthus nitens var. salicifolius Aqueous Extract Protects against 5-Fluorouracil Induced Gastrointestinal Mucositis in a Mouse Model

Figure 5

Histological and morphological change of small intestine. Small intestine from control (a), 5-Fu (b), 5-Fu + loperamide (c), and 5-Fu + CS aqueous extract at 20 g/kg (d) was prepared for H&E sections. Morphological assessment was performed using the image analysis program of Nikon Nis-element, and villus shortening was calculated by the average villus-to-crypts ratio (e) to evaluate the mucosal damage. Each bar represents the mean ± SEM (𝑛=8/group); ^∗∗∗𝑃<0.005.

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