6-Shogaol Protects against Oxidized LDL-Induced Endothelial Injruries by Inhibiting Oxidized LDL-Evoked LOX-1 Signaling

<table>Modulation of oxLDL-induced LOX-1 expression by 6-shogaol. Human umbilical vein endothelial cells (HUVECs) were exposed to 10, 30 <i>μ</i>M 6-shogaol, 5 <i>μ</i>M DPI, 200 <i>μ</i>g/mL oxidized low-density lipoprotein (oxLDL), and a combination of 6-shogaol and oxLDL. Cellular LOX-1 mRNA (a) and protein expression were immunodetected (b).</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 4

Figure 4: 6-Shogaol Protects against Oxidized LDL-Induced Endothelial Injruries by Inhibiting Oxidized LDL-Evoked LOX-1 Signaling 