Research Article

Gastroprotective Effects of Lion’s Mane Mushroom Hericium erinaceus (Bull.:Fr.) Pers. (Aphyllophoromycetideae) Extract against Ethanol-Induced Ulcer in Rats

Table 1

Effect of aqueous extract of H. erinaceus on different gastric parameters of ethanol-induced rats.

Animal groupsTreatment (5 mL/kg dose)Ulcer area (mm2)
Mean ± SEM
Ulcer inhibition (%)Mucus production (g)

1Non-treatment group00
2Ulcer control group
3Omeprazole (20 mg/kg)
4H. erinaceus (50 mg/kg)
5H. erinaceus (100 mg/kg)
6H. erinaceus (200 mg/kg)
7H. erinaceus (400 mg/kg)

All values were expressed as mean ± standard error of mean. *Significant difference ( ) when compared with the ulcer control (group 2). #Significant difference ( ) when compared with the omeprazole (group 3).