Electroacupuncture Attenuates 5′-Guanidinonaltrindole-Evoked Scratching and Spinal c-Fos Expression in the Mouse
Figure 11
Effects of EA on GNTI- (0.6 mg/kg) induced scratching behavior (a) and c-Fos expression (b). (a) Effects of EA 2 Hz (applied to the LI4 and LI11 acupoints) on GNTI- (0.6 mg/kg) induced scratches. The number of scratches was counted for 40 min after injection of GNTI. EA at 2 Hz reduced GNTI- (0.6 mg/kg) induced scratching behavior (* compared to control by Student’s -test). (b) The numbers of c-Fos positive nuclei were counted and averaged from 12 randomly chosen cervical sections from each animal in each group. EA at 2 Hz was applied to the LI4 and LI11 acupoints before administration of GNTI (0.6 mg/kg, s.c.). EA (2 Hz) significantly decreased the number of c-Fos positive nuclei (*, Student’s -test; : the number of animals).
