Astragalus Polysaccharide Suppresses the Expression of Adhesion Molecules through the Regulation of the p38 MAPK Signaling Pathway in Human Cardiac Microvascular Endothelial Cells after Ischemia-Reperfusion Injury
Figure 3
Rate of adhesion between endothelial cells and PMN. In contrast to 1 h oxygen deprivation alone, 1 h hypoxia followed by 6 h reperfusion increases the number of neutrophil granulocytes that adhered to HCMEC. Same result happens to comparison between 2 h hypoxia group and 2 h hypoxia followed by 6 h reperfusion group. Which means more neutrophil granulocyte adhere to HCMEC in latter group than in former group. However, things become different in 4 h hypoxia group and 4 h oxygen deprivation followed by 6 h reperfusion group. That is to say cohesion between neutrophil granulocytes and HCMEC in two groups is of no significant difference. ( versus the corresponding hypoxia-treated groups.)
