Astragalus Polysaccharide Suppresses the Expression of Adhesion Molecules through the Regulation of the p38 MAPK Signaling Pathway in Human Cardiac Microvascular Endothelial Cells after Ischemia-Reperfusion Injury
Figure 2
Viability of endothelial cells after ischemia-reperfusion. In contrast to 1 h oxygen deprivation alone, 1 h followed by 6 h reperfusion will not cause further injury to HCMEC; however, 24 h reperfusion would lead to apparent IRI to HCMEC. Compared with 2 h hypoxia alone, 2 h hypoxia followed by 6 h reperfusion or 12 h reperfusion both can result in IRI. In comparison with 4 h oxygen deprivation alone, 4 h hypoxia followed by 4 h reperfusion, 6 h reperfusion, or 24 h reperfusion all bring about similar influence on cell proliferation. (, versus the corresponding hypoxia-treated groups.)
